Which analgesic should be avoided in children due to risk of Reye syndrome?

• A. Aspirin
• B. Acetaminophen
• C. Ibuprofen
• D. Naproxen

Answer: (A)

Reye syndrome risk is tied to aspirin use in children. Reye syndrome is a rare but serious brain and liver condition that can occur after a viral illness such as influenza or chickenpox. Giving aspirin during or after these illnesses markedly increases that risk, so aspirin should be avoided in anyone under 18 for fever or pain. Safer alternatives for pediatric analgesia and fever include acetaminophen and ibuprofen, with naproxen as another NSAID option used cautiously. Always follow appropriate dosing and consider any specific health conditions or allergies when choosing an analgesic for a child.